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Merck
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Documentos clave

780200P

Avanti

16:0 PE MCC

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder

Sinónimos:

1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)

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About This Item

Fórmula empírica (notación de Hill):
C49H86N2O11PNa
Número de CAS:
384832-87-5
Peso molecular:
933.18
Código UNSPSC:
12352211
NACRES:
NA.25

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 25 mg (780200P-25mg)

fabricante / nombre comercial

Avanti Polar Lipids 780200P

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Categorías relacionadas

Descripción general

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (16:0 PE MCC) is a lipid consisting of phosphoethanolamine linked to two palmitic acid through its phosphate group and to a maleimide group by its amino group. It is a maleimide-functionalized lipid.

Aplicación

16:0 PE MCC (1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide]) may been used in functionalized liposome preparation for drug delivery. It may also be used in liposome preparation for testing drug delivery functionality and as a component in microbubble dispersions.

Acciones bioquímicas o fisiológicas

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide](DPPE-MCC) via the maleimide group enables covalent attachment in functionalized liposomes and is useful in peptide transport studies.

Envase

5 mL Amber Glass Screw Cap Vial (780200P-25mg)

Código de clase de almacenamiento

11 - Combustible Solids

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Astrid Hilde Myrset et al.
Ultrasound in medicine & biology, 37(1), 136-150 (2010-12-15)
Targeted ultrasound (US) contrast agents represent, because of their size (1 to 5 μm), a unique class of diagnostic imaging agents enabling true vascular imaging of conditions like inflammation and tumor angiogenesis. The objective of this study was to develop
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to

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