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KITALYSIS-SM

Sigma-Aldrich

KitAlysis™ High-Throughput Suzuki-Miyaura Cross-Coupling Reaction Screening Kit - Pack of 4

Sinónimos:

Suzuki-Miyaura Cross-Coupling

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About This Item

Código UNSPSC:
12161600
NACRES:
NA.22

idoneidad de la reacción

reaction type: Cross Couplings
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
core: palladium

grupo funcional

phosphine

Aplicación

Screening kit for Suzuki-Miyaura cross-coupling reaction. Step-by-step user guide and a downloadable experimental excel sheets are provided in the below hyperlink.
Step-by-Step Guide for Suzuki-Miyaura Cross-Coupling Reaction Screening Kit
Downloadable experimental excel sheet

Each kit contains 4 customizable screening sets that include the following components:
  • 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat.
  • 1 (2 mL) ampule each of Toluene, THF, n-Butanol, DMAc, and aq. 1.5 M K3PO4.
  • 4 NEW KitAlysis 24-Well Reaction Block Replacement Films.
  • 4 substrate reaction vials with stir bars.
  • 1 internal standard.
Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Características y beneficios

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reactions in parallel.
  • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration.
  • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Información legal

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Solo componentes del kit

Referencia del producto
Descripción
  • SnapIT Ampule Opener, Regular, for 1-2ml, 5-10ml, 10-15ml ampoules 1 EA

Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS
  • 732117Pd-PEPPSI™-IPent catalyst, ≥95% 5 µmolSDS
  • 753009SPhos Pd G2 5 µmolSDS
  • 761311cataCXium® A Pd G2 5 µmolSDS
  • 763381XPhos Pd G3, 98%, 1:1 MTBE adduct 5 µmolSDS
  • 764175P(Cy3) Pd G3, 97% 5 µmolSDS
  • 764183APhos Pd G3, 97% 5 µmolSDS
  • 900522Toluene, anhydrous, ZerO2®, 99.8% 8 mLSDS
  • 900636Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9% 8 mLSDS
  • 9006391-Butanol, anhydrous, ZerO2®, 99.8% 8 mLSDS
  • 900634N,N-Dimethylacetamide, anhydrous, ZerO2®, 99.8% 8 mLSDS
  • Degassed Potassium phosphate tribasic solution 8 mL
  • Z118850Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mm 1 EASDS
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Opcional

Referencia del producto
Descripción
Precios

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Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Órganos de actuación

Central nervous system, Respiratory system

Riesgos supl.

EUH019

Código de clase de almacenamiento

3 - Flammable liquids

Punto de inflamabilidad (°F)

1.4 °F

Punto de inflamabilidad (°C)

-17 °C

Listados normativos

Los listados normativos se proporcionan para los productos químicos principalmente. Para los productos no químicos sólo se puede proporcionar información limitada. Si no hay ninguna entrada, significa que ninguno de los componentes está en la lista. Es obligación del usuario garantizar el uso seguro y legal del producto.

EU REACH Annex XVII (Restriction List)

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

Lo sentimos, en este momento no disponemos de COAs para este producto en línea.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

High-Throughput Experimentation in Catalysis and Materials Science.
Gordillo A, et al.
Ullmann's Encyclopedia of Industrial Chemistry (2014)
Scientist-Led High-Throughput Experimentation (HTE) and Its Utility in Academia and Industry.
Schmink JR, et al.
Aldrichimica Acta, 46, 71-80 (2013)
Spencer D Dreher et al.
Journal of the American Chemical Society, 130(29), 9257-9259 (2008-06-28)
Microscale parallel experimentation was used to discover three catalyst systems capable of coupling secondary organotrifluoroborates with sterically and electronically demanding aryl chlorides and bromides. The ensuing results represent the first comprehensive study of alkylboron coupling to aryl chlorides and, in
Karl D Collins et al.
Nature chemistry, 6(10), 859-871 (2014-09-23)
New organic reactivity has often been discovered by happenstance. Several recent research efforts have attempted to leverage this to discover new reactions. In this Review, we attempt to unify reported approaches to reaction discovery on the basis of the practical

Artículos

Scale-Up Guide: Suzuki-Miyaura Cross-Coupling Reaction

All of the preformed catalysts used in the kit are air and moisture stable complexes in their commercially available form.

KitAlysis™ High-Throughput Screening Platform

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

KitAlysis™ Suzuki-Miyaura Cross-Coupling Reaction Screening Kit

Multiple tools have been created to ensure your success with kit set up. Start with the more detailed guide to ensure you are comfortable with all of the steps before using the quick guides on the excel worksheet. Remember that while the technique is new, it is still organic chemistry and so the steps will seem easy once you try just one kit. It is just a new way of approaching something you are already very good at.

KitAlysis High-Throughput Palladium Precatalyst Cross-Coupling Reaction Screening Kit

Materials Included in your KITALYSIS-24PD-2PK High-Throughput Screening Kit

Protocolos

Step-by-Step Guide for KitAlysis™ Suzuki-Miyaura Cross-Coupling Reaction Screening Kit

A step-by-step protocol guide for KitAlysis Suzuki-Miyaura Cross-Coupling Reaction Screening Kit.

Contenido relacionado

Reaction Design & Optimization

Chemical reaction design and optimization in organic synthesis aims to precisely alter reaction parameters to achieve optimum results in finding pathways to target molecules.

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