928321

BrettPhos Pd G3 ChemBeads

• Sinónimos: [(2-Di-cyclohexylphosphino-3,6-dimethoxy-2′,4′,6′- triisopropyl-1,1′-biphenyl)-2-(2′-amino-1,1′ -biphenyl)]palladium(II) methanesulfonate methanesulfonate
• Fórmula empírica (notación de Hill): C₄₈H₆₆NO₅PPdS
• Número de CAS: 1470372-59-8
• Peso molecular: 906.50
• Número MDL: MFCD22572666
• Código UNSPSC: 12352101
• NACRES: NA.82

Propiedades

• Análisis: ~5 wt.% loading of catalyst
• Nivel de calidad: 100
• formulario: solid
• idoneidad de la reacción: reagent type: catalyst; reaction type: Cross Couplings
• Extensión del etiquetado: ~5 wt. % loading of catalyst

Descripción

Descripción general

BrettPhos Pd G3 is a third generation (G3) Buchwald precatalyst. It is air, moisture and thermally-stable and is highly soluble in a wide range of common organic solvents. It has long life in solutions. BrettPhos Pd G3 is an excellent reagent for Buchwald-Hartwig cross-coupling reaction. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

For larger scale uses, product also available in powdered form (761605)

Aplicación

BrettPhos Pd G3 may be used for the C-N coupling reaction between monosubstituted ureas and 1,2 dihaloaromatic system to form benzimidazolones.It may be used in the synthesis of following compounds:

• [Pd(cinnamyl)(BrettPhos)]OTf by reacting with [(cinnamyl)PdCl]₂ and AgOTf.
• [Pd(crotyl)(BrettPhos)]OTf by reacting with [(crotyl)PdCl]₂ and AgOTf.
• [Pd(allyl)(BrettPhos)]OTf by reacting with [(allyl)PdCl]₂ and AgOTf.
• Pd(allyl)(BrettPhos)Cl by reacting with [(allyl)PdCl]₂.

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Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H350i
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Carc. 1B Inhalation
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3