922692
Poly(lactide-alt-glycolide)
average Mn 20,000, 50:50 (lactide:glycolide)
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About This Item
Fórmula lineal:
(C5H6O4)n
Código UNSPSC:
12162002
NACRES:
NA.23
Productos recomendados
formulario
powder
Nivel de calidad
cociente alimentación
50:50 (lactide:glycolide)
mol peso
average Mn 20,000
color
white to beige
temp. de almacenamiento
2-8°C
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Aplicación
Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1. Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
Common Poly(lactide-co-glycolide) (PLGA) is a biocompatible and biodegradable polymer that has been approved by the FDA for biomedical and pharmaceutical applications. PLGA based polymers are usually synthesized from copolymerization of glycolide (GA) and lactide (LA). However, the copolymerization of glycolide (GA) and Lactide (LA) typically results in broad composition ranges and a random block nature because of the much higher reactivity of GA and the drastic polymerization conditions. Thus, simple use of equimolar charges of GA and LA results in polymers containing longer glycolic blocks leads to poor solubility in common solvents.
Common Poly(lactide-co-glycolide) (PLGA) is a biocompatible and biodegradable polymer that has been approved by the FDA for biomedical and pharmaceutical applications. PLGA based polymers are usually synthesized from copolymerization of glycolide (GA) and lactide (LA). However, the copolymerization of glycolide (GA) and Lactide (LA) typically results in broad composition ranges and a random block nature because of the much higher reactivity of GA and the drastic polymerization conditions. Thus, simple use of equimolar charges of GA and LA results in polymers containing longer glycolic blocks leads to poor solubility in common solvents.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Certificados de análisis (COA)
Lot/Batch Number
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Synthesis of poly(D,L-lactic acid-alt-glycolic acid) from D,L-3-methylglycolide
Dong C M, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 38, 4179-4179 (2000)
Lin Yu et al.
Biomacromolecules, 12(4), 1290-1297 (2011-03-03)
This paper reports the influence of sequence structures of block copolymers composed of poly(lactic acid-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) on their thermogelling aqueous behaviors. A series of thermogelling PLGA-PEG-PLGA triblock copolymers with similar chemical compositions and block lengths
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