900865

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinónimos: Formyl sulfonyl fluoride TMS-Alkyne, Probe building block
• Fórmula empírica (notación de Hill): C₁₂H₁₃FO₃SSi
• Número de CAS: 2088829-01-8
• Peso molecular: 284.38
• Código UNSPSC: 12352200
• NACRES: NA.22

Propiedades

• Ensayo: ≥95%
• Formulario: powder or crystals
• idoneidad de la reacción: reaction type: click chemistry
• temp. de almacenamiento: −20°C
• cadena SMILES: O=CC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

Descripción

Aplicación

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Otras notas

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable