776874

K-Oxyma

97%

• Sinónimos: 2-Cyano-2-(hydroxyimino)acetic acid ethyl ester, potassium salt, Ethyl (hydroxyimino)cyanoacetate potassium salt
• Fórmula empírica (notación de Hill): C₅H₅KN₂O₃
• Número de CAS: 158014-03-0
• Peso molecular: 180.20
• Número MDL: MFCD26960809
• Código UNSPSC: 12352111
• ID de la sustancia en PubChem: 329767868
• NACRES: NA.22

Propiedades

• Análisis: 97%
• formulario: powder
• idoneidad de la reacción: reaction type: Addition Reactions
• mp: 141-147
• aplicaciones: peptide synthesis
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CCOC(/C(C#N)=N/[O-])=O.[K+]
• InChI: 1S/C5H6N2O3.K/c1-2-10-5(8)4(3-6)7-9;/h9H,2H2,1H3;/q;+1/p-1/b7-4+;
• Clave InChI: ZFBMUWGNRJITLS-KQGICBIGSA-M

Descripción

Aplicación

• Non-explosive replacement for HOBt and HOAt with at least comparable performance to HOAt
• Outperforms HOAt in sterically demanding peptide bond formations
• Compatible with carbodiimide-mediated; solution and solid phase peptide coupling;
• Less epimerization than HOBt in fragment condensation reactions
• K-salt especially useful in peptide coupling on mild acid-labile resins such as 2-chlorotrityl; leading to minimal to no cleavage of the peptide from the resin due to its more alkaline character
• K-salt has a higher melting point than OxymaPure

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable