556815

3-Ethyl-4-methyl-3-pyrrolin-2-one

97%

• Fórmula empírica (notación de Hill): C₇H₁₁NO
• Número de CAS: 766-36-9
• Peso molecular: 125.17
• Número MDL: MFCD00173861
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24879585
• NACRES: NA.22

Propiedades

• Ensayo: 97%
• mp: 100-104 °C (lit.)
• cadena SMILES: CCC1=C(C)CNC1=O
• InChI: 1S/C7H11NO/c1-3-6-5(2)4-8-7(6)9/h3-4H2,1-2H3,(H,8,9)
• Clave InChI: YCTNTSVMJWIYTQ-UHFFFAOYSA-N

Descripción

Descripción general

3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:

• allylamine, via palladium(II)-assisted cyclization
• 4-methoxybenzylamine, via a ring-closing-metathesis strategy
• 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one

Aplicación

3-Ethyl-4-methyl-3-pyrrolin-2-one (3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one) may be employed as a precursor for the synthesis of glimepiride (antidiabetic drug) and its derivatives (sulfonylurea drugs). It may also be employed for the preparation of 2-ethyl-3-methyl-(10H)-
dipyrrin-1-one.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)