512125

3-Pyridinylboronic acid

≥95.0%

• Sinónimos: 3-Pyridineboronic acid, 3-Pyridylboronic acid, Dihydroxy(3-pyridyl)borane, Pyridin-3-ylboronic acid
• Fórmula empírica (notación de Hill): C₅H₆BNO₂
• Número de CAS: 1692-25-7
• Peso molecular: 122.92
• Número MDL: MFCD00674177
• Código UNSPSC: 12352103
• ID de la sustancia en PubChem: 24873612
• NACRES: NA.22

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥95.0%
• Formulario: solid
• mp: >300 °C (lit.)
• cadena SMILES: OB(O)c1cccnc1
• InChI: 1S/C5H6BNO2/c8-6(9)5-2-1-3-7-4-5/h1-4,8-9H
• Clave InChI: ABMYEXAYWZJVOV-UHFFFAOYSA-N

Descripción

Aplicación

3-Pyridinylboronic acid can be used as a reagent for:

• Phosphine-free Suzuki-Miyaura cross-coupling reactions.
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation.
• N-arylation using copper acetylacetonate catalyst.
• Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes.

It can also be used to prepare:

• New linear poly(phenylpyridyl) chains by Suzuki coupling.
• Oligopyridyl foldamers as mimics of a-helix twist.
• Many highly significant therapeutic enzymatic and kinase inhibitors and receptor antagonists.
• Pyridine substituted pyridinium N-(2′-azinyl)aminides by reacting with dibromo pyridinium aminides via Suzuki coupling reaction.

Otras notas

Contains varying amounts of anhydride

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)