392731

(DHQD)₂PHAL

≥95%

• Sinónimos: Hydroquinidine 1,4-phthalazinediyl diether
• Fórmula empírica (notación de Hill): C₄₈H₅₄N₆O₄
• Número de CAS: 140853-10-7
• Peso molecular: 778.98
• Beilstein: 5475678
• Número MDL: MFCD00198107
• Código UNSPSC: 12352005
• ID de la sustancia en PubChem: 24864481
• NACRES: NA.22

Propiedades

• Análisis: ≥95%
• formulario: powder
• actividad óptica: [α]22/D −262°, c = 1.2 in methanol
• puntuación de productos alternativos más sostenibles: old score: 5; new score: 3; Find out more about DOZN™ Scoring
• características de los productos alternativos más sostenibles: Waste Prevention; Less Hazardous Chemical Syntheses; Safer Solvents and Auxiliaries; Inherently Safer Chemistry for Accident Prevention; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 160 °C (dec.) (lit.)
• categoría alternativa más sostenible: , Re-engineered
• cadena SMILES: CC[C@H]1CN2CCC1CC2[C@@H](Oc3nnc(O[C@H](C4CC5CCN4C[C@@H]5CC)c6ccnc7ccc(OC)cc67)c8ccccc38)c9ccnc%10ccc(OC)cc9%10
• InChI: 1S/C48H54N6O4/c1-5-29-27-53-21-17-31(29)23-43(53)45(35-15-19-49-41-13-11-33(55-3)25-39(35)41)57-47-37-9-7-8-10-38(37)48(52-51-47)58-46(44-24-32-18-22-54(44)28-30(32)6-2)36-16-20-50-42-14-12-34(56-4)26-40(36)42/h7-16,19-20,25-26,29-32,43-46H,5-6,17-18,21-24,27-28H2,1-4H3/t29-,30-,31-,32-,43+,44+,45-,46-/m0/s1
• Clave InChI: YUCBLVFHJWOYDN-HVLQGHBFSA-N

Descripción

Descripción general

(DHQD)₂PHAL is a dimer that can be used as a chiral amine catalyst for asymmetric halogenations.

(DHQD)₂PHAL is a modified cinchona alkaloid derivative mainly used as a ligand for enantioselective catalysis.

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Less Hazardous Chemical Syntheses”, "Safer Solvents and Auxiliaries" and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard.

Aplicación

(DHQD)₂PHAL may be used as ligand for:

• Osmium trioxide catalyzed asymmetric dihydroxylation of olefins.
• Palladium catalyzed Suzuki-Miyaura coupling of aryl/heteroaryl halides with aryl boronic acids in aqueous medium and in the absence of phosphine/organic solvent.
• Copper(I)-catalyzed azide-alkyne cycloaddition reaction to synthesize 1,2,3-triazoles in water.

Hydroquinidine 1,4-phthalazinediyl diether [(DHQD)₂PHAL] can be used:

• As a ligand for Sharpless asymmetric dihydroxylation.
• For enantioselective α-fluorination of carbonyl compounds.

Información legal

Sold under license from Rhodia Pharma Solutions.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)