PADI2
peptidyl arginine deiminase, type II
Sinónimos:
PAD-H19, PAD2, PDI2
Especie:
Human PADI2 (11240), Mouse Padi2 (18600), Rat Padi2 (29511), Zebrafish padi2 (386792), cow PADI2 (617851), Horse PADI2 (100050025), domestic cat PADI2 (101085301), chicken PADI2 (428172), dog PADI2 (487414), naked mole-rat Padi2 (101721485) ...Más
ID UniProtKB:
ID del gen:
- Human(11240) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
- Mouse(18600) peptidyl arginine deiminase, type II
- Rat(29511) peptidyl arginine deiminase, type II
- Zebrafish(386792) peptidyl arginine deiminase, type II
- cow(617851) peptidyl arginine deiminase, type II
- Horse(100050025) peptidyl arginine deiminase, type II
- domestic cat(101085301) peptidyl arginine deiminase, type II
- chicken(428172) peptidyl arginine deiminase, type II
- dog(487414) peptidyl arginine deiminase, type II
- naked mole-rat(101721485) peptidyl arginine deiminase, type II
- domestic guinea pig(100728531) peptidyl arginine deiminase, type II
- sheep(101108464) peptidyl arginine deiminase, type II
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PADI2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-PADI2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, horse, human
Aplicación
western blot
Anti-PADI2/PAD2 Antibody, clone DN2, ,
Reactividad de especies
human, rabbit
Aplicación
ELISA
immunohistochemistry
multiplexing
western blot
immunohistochemistry
multiplexing
western blot
Proteins
Referencia del producto
Descripción
Especie
PAD2, GST tagged from mouse, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
mouse
PADI-2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE),
Especie
human