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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Sinónimos:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Especie:
Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), chicken HTR3A (428247), cow HTR3A (617674), Horse HTR3A (100009690), domestic cat HTR3A (101098004), dog HTR3A (489399), domestic guinea pig Htr3a (100135547), naked mole-rat Htr3a (101714088) ...Más
ID UniProtKB:
P46098, B4DSY6, G5E986, O60854, Q7KZM7, Q99918, Q9BSZ9
ID del gen:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
32473
Metoclopramide, VETRANAL®, analytical standard,
Especie
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Especie
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
S1688
SR 57227A, solid,
Especie
human
M0763
Metoclopramide hydrochloride, solid,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
H9523
Serotonin hydrochloride, powder,
Especie
human
H7752
Serotonin creatinine sulfate monohydrate, powder,
Especie
human
O3639
Ondansetron hydrochloride dihydrate, ≥98% (HPLC), powder,
Especie
human
PHR1141
Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
73659
1-(4-Chlorophenyl)piperazine, ≥98.0% (GC),
Especie
rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA069442
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
ABN1475
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Especie
human
Z101
Zimelidine dihydrochloride, solid,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Especie
human
F132
Fluoxetina hydrochloride, solid,
Especie
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Especie
human
R0875
Reserpine, ,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU053551
MISSION® esiRNA, targeting mouse Htr3a,
Especie
mouse
EHU080571
MISSION® esiRNA, targeting human HTR3A,
Especie
human