Skip to Content
Merck
All Photos(4)

Documents

N6125

Sigma-Aldrich

Naphthol AS-TR phosphate disodium salt

fluorogenic, ≥99% (HPLC), powder

Synonym(s):

NASTRp disodium salt

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Empirical Formula (Hill Notation):
C18H13ClNNa2O5P
CAS Number:
4264-93-1
Molecular Weight:
435.71
MDL number:
MFCD00069550
UNSPSC Code:
12352204
PubChem Substance ID:
24897766
NACRES:
NA.83

product name

Naphthol AS-TR phosphate disodium salt, ≥99% (HPLC), Bulk package

Assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

[Na+].[Na+].Cc1cc(Cl)ccc1NC(=O)c2cc3ccccc3cc2OP([O-])([O-])=O

InChI

1S/C18H15ClNO5P.2Na/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24;;/h2-10H,1H3,(H,20,21)(H2,22,23,24);;/q;2*+1/p-2

InChI key

TYCHZTPSWMGRRI-UHFFFAOYSA-L

Looking for similar products? Visit Product Comparison Guide

Application

Substrate for the histochemical demonstration of acid and alkaline phosphatase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Adéla Kratochvílová et al.
Scientific reports, 10(1), 7489-7489 (2020-05-06)
Caspases are proteases traditionally associated with inflammation and cell death. Recently, they have also been shown to modulate cell proliferation and differentiation. The aim of the current research was to search for osteogenic molecules affected by caspase inhibition and to specify
Eva Svandova et al.
Journal of anatomy, 235(2), 256-261 (2019-05-31)
FASL (CD178) is known for its role in triggering apoptosis, mostly in relation with immune cells but additional functions have been reported more recently, including those in bone development. Examination of postnatal FasL-deficient mice (gld) showed an increased bone deposition
Claire Chevalier et al.
STAR protocols, 2(2), 100452-100452 (2021-04-30)
Mesenchymal-derived osteoblasts play a key role in bone formation via synthesis and mineralization of the bone and bone remodeling. Osteoclasts are multinucleated cells of hematopoietic origin with a role in bone resorption. Here, we describe a protocol for generating primary
Veronika Oralová et al.
Biology open, 8(5) (2019-05-28)
Zebrafish is now widely used in biomedical research as a model for human diseases, but the relevance of the model depends on a rigorous analysis of the phenotypes obtained. Many zebrafish disease models, experimental techniques and manipulations take advantage of
Claire Chevalier et al.
Cell metabolism, 32(4), 575-590 (2020-09-12)
Osteoporosis is the most prevalent metabolic bone disease, characterized by low bone mass and microarchitectural deterioration. Here, we show that warmth exposure (34°C) protects against ovariectomy-induced bone loss by increasing trabecular bone volume, connectivity density, and thickness, leading to improved
View All Related Papers

Articles

Colorimetric Alkaline Phosphatase and Peroxidase Substrate Detection Systems

Nitroblue Tetrazolium (NBT) is used with the alkaline phosphatase substrate 5-Bromo- 4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures. These substrate systems produce an insoluble NBT diformazan end product that is blue to purple in color and can be observed visually.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service