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8.51023

Sigma-Aldrich

Biotin-OSu

Novabiochem®

Synonym(s):

Biotin-OSu, N-(Biotinyloxy)succinimide

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O5S
CAS Number:
Molecular Weight:
341.38
MDL number:
UNSPSC Code:
12352108

Quality Level

product line

Novabiochem®

Assay

≥97% (TLC)
≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Biotinylations

manufacturer/tradename

Novabiochem®

mp

206-207 °C

application(s)

peptide synthesis

storage temp.

15-25°C

InChI

1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)

InChI key

YMXHPSHLTSZXKH-UHFFFAOYSA-N

General description

Pre-activated reagent for the introduction of biotin by solid phase synthesis.

Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Linkage

Replaces: 01-63-0106

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): 48.5 - 55.5 °
Purity (TLC(011B)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (50 mg in 1 ml NMP): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Biotin-labelled peptides have many important applications in immunology and histochemistry, such as affinity purification and FRET-based flow cytometry, solid-phase immunoassays, and receptor localization, that exploit the high affinity of streptavidin and avidin for biotin.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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