SML3933

CLC-2 channel inhibitor, AK-42

≥98% (HPLC)

• Synonym(s): 2-[[2,6-Dichloro-3-(phenylmethoxy)phenyl]amino]-3-pyridinecarboxylic acid, AK-42
• Empirical Formula (Hill Notation): C₁₉H₁₄Cl₂N₂O₃
• CAS Number: 2408824-56-4
• Molecular Weight: 389.23
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C
• SMILES string: O=C(C1=C(NC2=C(Cl)C=CC(OCC3=CC=CC=C3)=C2Cl)N=CC=C1)O
• InChI: 1S/C19H14Cl2N2O3/c20-14-8-9-15(26-11-12-5-2-1-3-6-12)16(21)17(14)23-18-13(19(24)25)7-4-10-22-18/h1-10H,11H2,(H,22,23)(H,24,25)

Description

Biochem/physiol Actions

Specific and potent CLC-2 chloride channel inhibitor that binds to the CLC-2 channel extracellularly.



CLC-2 channel inhibitor AK-42 is a specific and potent CLC-2 chloride channel inhibitor that binds to the CLC-2 channel extracellularly. AK-42 causes selective and reversible blocking of CLC-2 currents.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable