SML3598
1PBC
≥98% (HPLC)
Synonym(s):
1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
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About This Item
Empirical Formula (Hill Notation):
C13H6F3N3O
CAS Number:
Molecular Weight:
277.20
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
-10 to -25°C
SMILES string
OC1=CC(C(F)(F)F)=C(C#N)C2=NC3=CC=CC=C3N21
Biochem/physiol Actions
1PBC is a potent and selective blocker of TMEM16A calcium-activated chloride channel that interacts with the anion pore. Also, 1PBC is a potent inhibitor of TMEM16F channel.
Potent and selective blocker of TMEM16A calcium-activated chloride channel; potent inhibitor of TMEM16F channel
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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