Skip to Content
Merck
All Photos(1)

Key Documents

SCP0096

Sigma-Aldrich

Caspase Substrate

Synonym(s):

Ac-LETD-AFC, Ac-Leu-Glu-Thr-Asp-7-amino-4-trifluoromethyl coumarin

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C31H38N5O12
Molecular Weight:
672.66
UNSPSC Code:
12352202
NACRES:
NA.32

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP8(841)

Amino Acid Sequence

Ac-Leu-Glu-Thr-Asp-AFC

Biochem/physiol Actions

The peptide Ac-Leu-Glu-Thr-Asp-AFC, or Ac-LETD-AFC, is a fluorogenic substrate for caspase-8. The tetrapeptide sequence LETD is recognized as an ideal cleavage sequence for caspase-8.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service