57858

Sodium iodoacetate

BioUltra, ≥99.5% (NT)

• Synonym(s): Iodoacetic acid sodium salt
• Linear Formula: ICH₂COONa
• CAS Number: 305-53-3
• Molecular Weight: 207.93
• Beilstein: 4009322
• EC Number: 206-165-7
• MDL number: MFCD00002686
• UNSPSC Code: 12352106
• PubChem Substance ID: 57651633
• NACRES: NA.26

Properties

• product line: BioUltra
• Quality Level: 100
• Assay: ≥99.5% (NT)
• impurities: insoluble matter, passes filter test; ≤0.5% water
• mp: 208 °C (dec.) (lit.)
• solubility: methanol: 0.1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤500 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: cut-off at 335 nm in methanol at 0.1 M
• storage temp.: −20°C
• SMILES string: [Na+].[O-]C(=O)CI
• InChI: 1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
• InChI key: AGDSCTQQXMDDCV-UHFFFAOYSA-M

Description

Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

Other Notes

Sulfhydryl reagent

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H314
• Precautionary Statements: P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 406.4 °F
• Flash Point(C): 208 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves