T7697

I-OMe-Tyrphostin AG 538

solid

• Synonym(e): α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone, I-OMe-AG 538
• Empirische Formel (Hill-System): C₁₇H₁₂INO₅
• CAS-Nummer: 1094048-77-7
• Molekulargewicht: 437.19
• MDL-Nummer: MFCD03453582
• UNSPSC-Code: 12352203
• PubChem Substanz-ID: 24278758
• NACRES: NA.77

Eigenschaften

• Form: solid
• Löslichkeit: DMSO: 50 mg/mL
• Lagertemp.: −20°C
• SMILES String: COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2
• InChI: 1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+
• InChIKey: HSRMHXWCTRFVHK-NYYWCZLTSA-N
• Angaben zum Gen: human ... IGF1(3479) , IGF1R(3480)

Beschreibung

Anwendung

I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors.

Biochem./physiol. Wirkung

Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor.

Leistungsmerkmale und Vorteile

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Angaben zur Herstellung

I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)