Direkt zum Inhalt
Merck
Alle Fotos(1)

Key Documents

View All Documentation

T3955

Sigma-Aldrich

TNP

≥95% (HPLC)

Synonym(e):

N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):
C20H16F3N7O2
CAS-Nummer:
519178-28-0
Molekulargewicht:
443.38
MDL-Nummer:
MFCD16875436
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329826781
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥95% (HPLC)

Form

powder

Lagerbedingungen

protect from light

Farbe

yellow

Löslichkeit

DMSO: ≥10 mg/mL

Ersteller

Novartis

Lagertemp.

2-8°C

SMILES String

[O-][N+](=O)c1ccc(CNc2nc(NCc3cccc(c3)C(F)(F)F)nc4[nH]cnc24)cc1

InChI

1S/C20H16F3N7O2/c21-20(22,23)14-3-1-2-13(8-14)10-25-19-28-17(16-18(29-19)27-11-26-16)24-9-12-4-6-15(7-5-12)30(31)32/h1-8,11H,9-10H2,(H3,24,25,26,27,28,29)

InChIKey

DDSBPUYZPWNNGH-UHFFFAOYSA-N

Biochem./physiol. Wirkung

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

Leistungsmerkmale und Vorteile

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Angaben zur Herstellung

TNP is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 2

1 of 2

Pikrinsäure moistened with water, ≥98%

Sigma-Aldrich

197378

Pikrinsäure

Quercetin ≥95% (HPLC), solid

Sigma-Aldrich

Q4951

Quercetin

Maxime Dupin et al.
PloS one, 6(6), e20957-e20957 (2011-06-28)
Many distribution models developed to predict the presence/absence of invasive alien species need to be fitted to a training dataset before practical use. The training dataset is characterized by the number of recorded presences/absences and by their geographical locations. The
Joerg U Eberle et al.
The Journal of investigative dermatology, 139(9), 1957-1965 (2019-03-27)
The mechanisms leading to allergic skin inflammation, such as atopic dermatitis or urticaria, are poorly defined. Here we used a mouse model for IgE-dependent chronic allergic inflammation to study the role of basophils and eosinophils for induction of pathology. FcεRI
Takashi Nakagata et al.
Medicina (Kaunas, Lithuania), 55(7) (2019-07-10)
Background and objectives: Exercise can help ease withdrawal symptoms of smokers. However, there is little information about the physiological responses, such as cardiorespiratory and lactate (La) responses, during exercise from light to moderate intensity combined with transdermal nicotine patches (TNPs)
Jo-Anne E Cavanagh et al.
Toxicology in vitro : an international journal published in association with BIBRA, 48, 342-349 (2018-02-11)
The use of biosolids as a soil conditioner and fertiliser is hindered by the limited knowledge on the risks of micro-contaminants they contain. This study investigated the binding of six organic contaminants commonly found in biosolids, to the estrogen (ER)
Natalie E Nieuwenhuizen et al.
PLoS neglected tropical diseases, 7(8), e2395-e2395 (2013-09-07)
Nematode secreted haemoglobins have unusually high affinity for oxygen and possess nitric oxide deoxygenase, and catalase activity thought to be important in protection against host immune responses to infection. In this study, we generated a monoclonal antibody (48Eg) against haemoglobin
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.