SML3158

6-Methylflavon

≥98% (HPLC)

• Synonym(e): 6-Methyl-2-phenyl-4H-1-benzopyran-4-one, 6-Methyl-2-phenyl-4H-chromen-4-one
• Empirische Formel (Hill-System): C₁₆H₁₂O₂
• CAS-Nummer: 29976-75-8
• Molekulargewicht: 236.27
• MDL-Nummer: MFCD00017461
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• mp (Schmelzpunkt): 119-122 °C (dec.) (lit.)
• Löslichkeit: DMSO: 2 mg/mL, clear (warmed)
• Lagertemp.: 2-8°C
• SMILES String: Cc1ccc2OC(=CC(=O)c2c1)c3ccccc3
• InChI: 1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3
• InChIKey: NOQJBXPAMJLUSS-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir alafenamide. 6-Methylflavone is a positive allosteric modulator (PAM) of α1β2γ2L and α1β2 GABAA receptors.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable