SML2554

RIPK2 inhibitor 1

≥98% (HPLC)

• Synonym(e): 3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-benzamide, MolPort-016-359-762
• Empirische Formel (Hill-System): C₂₅H₂₂N₄O₂
• CAS-Nummer: 1290490-78-6
• Molekulargewicht: 410.47
• MDL-Nummer: MFCD31746634
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to very dark gray
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: CC1=CC=C(C(NC2=CC(C3=NC=CN3C)=CC=C2)=O)C=C1NC(C4=CC=CC=C4)=O
• InChI: 1S/C25H22N4O2/c1-17-11-12-20(16-22(17)28-24(30)18-7-4-3-5-8-18)25(31)27-21-10-6-9-19(15-21)23-26-13-14-29(23)2/h3-16H,1-2H3,(H,27,31)(H,28,30)
• InChIKey: OIIYBZHRYXJCHR-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models.

potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable