SML0014

Scutellarin hydrate

≥98% (HPLC)

• Synonym(e): 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-ß-D-glucopyranosiduronic acid hydrate, 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate, Breviscapin, Scutellarein-7-O-β-D-glucuronide
• Empirische Formel (Hill-System): C₂₁H₁₈O₁₂ · xH₂O
• CAS-Nummer: 27740-01-8
• Molekulargewicht: 462.36 (anhydrous basis)
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: yellow
• Löslichkeit: DMSO: ≥10 mg/mL
• Lagertemp.: 2-8°C

Beschreibung

Anwendung

Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.

Biochem./physiol. Wirkung

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

Leistungsmerkmale und Vorteile

This compound is featured on the MAPKs and Nitric Oxide Synthases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable