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SAB4700884

Sigma-Aldrich

Monoclonal Anti-CD45R antibody produced in rat

clone RA3-6B2

Synonym(e):

PTPRCR, T200R

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rat

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

RA3-6B2, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

cat, human, mouse

Konzentration

1 mg/mL

Methode(n)

flow cytometry: 2 μg/mL

Hinterlegungsnummer

NM_001111316.2

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Ptprc(19264)

Verwandte Kategorien

Allgemeine Beschreibung

The rat monoclonal antibody RA3-6B2 recognizes an epitope on CD45R, which is expressed at all developmental stages of B cells, including activated B cells, but also on subsets of NK and T cells. T cells detected by this antibody are supposed to be in activated state.

Immunogen

Abelson murine leukemia virus-induced pre-B tumor cells

Physikalische Form

Solution in phosphate buffered saline with 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Kelly A McGlynn et al.
Experimental hematology, 85, 20-32 (2020-05-22)
Mds1-Evi1 (also known as Prdm3) and Prdm16 are two highly related zinc finger transcription factors that, within the hematopoietic system, are both expressed primarily in hematopoietic stem cells (HSCs). Our laboratory previously found that constitutive Mds1-Evi1 knockout mice are viable
Federica Barbagallo et al.
International journal of molecular sciences, 21(8) (2020-04-25)
Phosphodiesterase 2A (PDE2A) is a cAMP-cGMP hydrolyzing enzyme essential for mouse development and the PDE2A knockout model (PDE2A-/-) is embryonic lethal. Notably, livers of PDE2A-/- embryos at embryonic day 14.5 (E14.5) have extremely reduced size. Morphological, cellular and molecular analyses
Marc Y Stevens et al.
Journal of neuroinflammation, 17(1), 275-275 (2020-09-20)
B cells play a central role in multiple sclerosis (MS) through production of injurious antibodies, secretion of pro-inflammatory cytokines, and antigen presentation. The therapeutic success of monoclonal antibodies (mAbs) targeting B cells in some but not all individuals suffering from
Laia Richart et al.
Oncogene, 39(25), 4884-4895 (2020-05-27)
Chromatin remodeling factors contribute to establish aberrant gene expression programs in cancer cells and therefore represent valuable targets for therapeutic intervention. BPTF (Bromodomain PhD Transcription Factor), a core subunit of the nucleosome remodeling factor (NURF), modulates c-MYC oncogenic activity in
Edie I Crosse et al.
Cell stem cell, 27(5), 822-839 (2020-09-19)
Hematopoietic stem cells (HSCs) first emerge in the embryonic aorta-gonad-mesonephros (AGM) region. Studies of model organisms defined intersecting signaling pathways that converge to promote HSC emergence predominantly in the ventral domain of the dorsal aorta. Much less is known about

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