SAB4504690

Anti-phospho-Bax (pSer¹⁸⁴) antibody produced in rabbit

affinity isolated antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 21 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:10000; immunohistochemistry: 1:50-1:100
• NCBI-Hinterlegungsnummer: Q07812
• UniProt-Hinterlegungsnummer: Q07812
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer184)
• Angaben zum Gen: human ... BAX(581)

Beschreibung

Allgemeine Beschreibung

Bif-1 (BAX-interacting factor 1), a membrane-curvature inducing protein is located on human chromosome 19q13. Bif-1 is also known as SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1)/ Endophilin B1. It belongs to the membrane curvature-driving endophilin protein family.

Immunogen

The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.

Immunogen Range: 143-192

Biochem./physiol. Wirkung

Bif-1 (BAX-interacting factor 1) plays a vital role in apoptosis. BAX gene may act as a negative regulator of autophagy in CRC (Colorectal cancer) development. Lack of Bif-1 affects lipid homeostasis and results in obesity followed by insulin resistance.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable