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Key Documents

RAB0689

Sigma-Aldrich

Human IL36G / Interleukin-36 Gamma ELISA Kit

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable

Aufnahme

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 13 pg/mL
standard curve range: 12.29-3000 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... IL36G(56300)

Verwandte Kategorien

Allgemeine Beschreibung

The IL36G ELISA kit provides for the Quantitative measurement of IL-36 gamma in Cell Culture Supernatants, Plasma and Serum.
Interleukin-36 gamma (IL36G), also known as IL-1F9, is a member of interleukin (IL)-1-like proinflammatory cytokine family. It is encoded by the gene mapped to human chromosome 2q12-q21. IL36G is abundantly expressed in epithelial tissues and numerous myeloid-derived cell types.

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem./physiol. Wirkung

Members of interleukin (IL)-1 family of cytokines play a vital role in regulating immune responses to infectious challenges and sterile insults. IL-36 is implicated in mucosal immunity, such as lung anti-bacterial responses. Interleukin-36 γ (IL36G) participates in inflammation response and differentiation. Overexpression of IL36G has been observed in psoriasis patients. Thus, down regulation IL36G can be considered as an effective method to treat psoriasis.

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB
  • RABSTOP3ELISA Stop Solution (Item I)SDB
  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Participation of interleukin family 1 in the development of inflammatory reaction in the infectious process. 1. General characteristics of the interleukin family 1.
Abaturov AE, et al.
CHILDS HEALTH (2014)
IL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasis.
Wang W, et al.
International Journal of Medical Sciences, 14(10), 1002-1002 (2017)
IL-1 family cytokines in cardiovascular disease.
Pfeiler S, et al.
Cytokine (2017)
IL-36γ is a crucial proximal component of protective type-1-mediated lung mucosal immunity in Gram-positive and-negative bacterial pneumonia.
Kovach MA, et al.
Mucosal Immunology, 10(5), 1320-1320 (2017)
Jennifer Mildenberger et al.
Autophagy, 13(10), 1664-1678 (2017-08-19)
Inflammation is crucial in the defense against infections but must be tightly controlled to limit detrimental hyperactivation. Our diet influences inflammatory processes and omega-3 polyunsaturated fatty acids (n-3 PUFAs) have known anti-inflammatory effects. The balance of pro- and anti-inflammatory processes

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