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P3029

Sigma-Aldrich

Phencyclidin -hydrochlorid

Synonym(e):

1-(1-Phenylcyclohexyl)-piperidin -hydrochlorid, PCP -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C17H25N · HCl
CAS-Nummer:
956-90-1
Molekulargewicht:
279.85
MDL-Nummer:
MFCD00058208
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329820160
NACRES:
NA.77

Form

powder

Qualitätsniveau

300

Arzneimittelkontrolle

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

Löslichkeit

H2O: 11.2 mg/mL
0.1 M HCl: 18.4 mg/mL
methanol: 30 mg/mL

SMILES String

Cl.C1CCN(CC1)C2(CCCCC2)c3ccccc3

InChI

1S/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H

InChIKey

BUAJNGPDPGKBGV-UHFFFAOYSA-N

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Biochem./physiol. Wirkung

σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.

Leistungsmerkmale und Vorteile

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Nicotinic) and Glutamate Receptors (Ion Channel Family) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301,H336

Gefahreneinstufungen

Acute Tox. 3 Oral - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Journal of neurochemistry, 64(2), 614-623 (1995-02-01)
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Journal of medicinal chemistry, 55(16), 7141-7153 (2012-08-01)
Functionally selective G protein-coupled receptor (GPCR) ligands, which differentially modulate canonical and noncanonical signaling, are extremely useful for elucidating key signal transduction pathways essential for both the therapeutic actions and side effects of drugs. However, few such ligands have been
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Schizophrenia bulletin, 38(5), 942-949 (2012-08-18)
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