O9139

N-(3-Oxododecanoyl)-L-homoserine lactone

≥98% (TLC)

• Synonym(e): 3-Oxo-C₁₂-HSL
• Empirische Formel (Hill-System): C₁₆H₂₇NO₄
• CAS-Nummer: 168982-69-2
• Molekulargewicht: 297.39
• MDL-Nummer: MFCD08275140
• UNSPSC-Code: 12352209
• eCl@ss: 32160406
• PubChem Substanz-ID: 329818935
• NACRES: NA.26

Eigenschaften

• Produktbezeichnung: N-(3-Oxododecanoyl)-L-homoserine lactone, quorum sensing signaling molecule
• Qualitätsniveau: 200
• Assay: ≥98% (TLC)
• Form: powder
• Farbe: white
• Anwendung(en): cell analysis
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: CCCCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
• InChI: 1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1
• InChIKey: PHSRRHGYXQCRPU-AWEZNQCLSA-N

Beschreibung

Anwendung

N-(3-Oxododecanoyl)-L-homoserine lactone (3-Oxo-C12-HSL), a member of a family of acyl homoserine lactones, may be used to determine its mechanisms and specificity of action as a signaling molecule involved in the regulation of bacterial quorum sensing.

Biochem./physiol. Wirkung

N-(3-oxododecanoyl)homoserine-L-lactone (3-oxo-C12-HSL) is among a group of homoserine lactones that includes: N-octanoyl-homoserine lactone (N-C8-HSL), N-(3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL), N-(3-Oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL, N-(3-hydroxydecanoyl)-L-homoserine lactone, and N-(3-hydroxyoctanoyl)-L-homoserine lactone involved in the processes of bacterial quorum sensing. These N-acyl-homoserine lactones are used to study the processes and mechanisms of bacterial quorum sensing.

Acyl homoserine lactone that is an autoinducer of quorum sensing by Pseudomonas aeruginosa. Degraded by paraoxonase (PON) family members.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves