44558

N-Octanoyl-L-Homoserinlacton

≥96% (HPLC)

• Synonym(e): N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamid, C8-HSL
• Empirische Formel (Hill-System): C₁₂H₂₁NO₃
• CAS-Nummer: 147852-84-4
• Molekulargewicht: 227.30
• Beilstein: 8148282
• MDL-Nummer: MFCD11113139
• UNSPSC-Code: 12352211
• PubChem Substanz-ID: 329756519
• NACRES: NA.85

Eigenschaften

• product name: N-Octanoyl-L-Homoserinlacton, ≥96% (HPLC)
• Assay: ≥96% (HPLC)
• Form: powder or crystals
• Optische Aktivität: [α]/D -28±3°, c = 0.2 in methanol
• Farbe: white to off-white
• Eignung: conforms to structure for Proton NMR spectrum
• Anwendung(en): detection
• Lagertemp.: −20°C
• SMILES String: O=C1OCC[C@@H]1NC(CCCCCCC)=O
• InChI: 1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
• InChIKey: JKEJEOJPJVRHMQ-JTQLQIEISA-N

Beschreibung

Biochem./physiol. Wirkung

N-Octanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, colonization, chemical defense and cell to cell communication among bacteria; for reviews see. AHLs are released as oligopeptides in Gram positive bacteria and as quorum signal in Gram negative bacteria. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.

Quorum-sensing signal generation

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable