O0383

N-Oleoylethanolamine

~98% (TLC)

• Synonym(e): N-(Hydroxyethyl)oleamide, N-(cis-9-Octadecenoyl)ethanolamine, OEA, oleoylethanolamide
• Empirische Formel (Hill-System): C₂₀H₃₉NO₂
• CAS-Nummer: 111-58-0
• Molekulargewicht: 325.53
• EG-Nummer: 203-884-8
• MDL-Nummer: MFCD00045972
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 24278603
• NACRES: NA.83

Eigenschaften

• Assay: ~98% (TLC)
• Form: powder
• Löslichkeit: chloroform: 20 mg/mL, clear, colorless
• Lagertemp.: −20°C
• SMILES String: O=C(CCCCCCC/C=C\CCCCCCCC)NCCO
• InChI: 1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
• InChIKey: BOWVQLFMWHZBEF-KTKRTIGZSA-N
• Angaben zum Gen: human ... CNR1(1268) , CNR2(1269) , PPARA(5465) , TRPV1(7442) ; mouse ... Cnr2(12802) ; rat ... Cnr1(25248)

Beschreibung

Allgemeine Beschreibung

Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine. Small intestine cells, adipose tissues, neurons and astrocytes produces OEA.

Anwendung

N-Oleoylethanolamine has been used to study its effects on glucagon-like peptide (GLP)-1RA-mediated anorectic signaling and weight loss.

Biochem./physiol. Wirkung

Oleoylethanolamide (OEA) is a lipid mediator, which helps to control various biological functions, like food intake. It modulates the gene expression in the small intestine. OEA has the ability to initiate several receptors, such as cannabinoid receptor type 1 (CB1), peroxisome proliferator-activated receptors (PPARs) and G protein-coupled receptor 119 (GPR119).

Peroxisome proliferator-activator receptor α (PPARα) agonist

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves