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3-Nitro-L-Tyrosin
crystalline
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About This Item
Lineare Formel:
O2NC6H3-4-(OH)CH2CH(NH2)CO2H
CAS-Nummer:
Molekulargewicht:
226.19
Beilstein:
2813157
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
eCl@ss:
32160406
PubChem Substanz-ID:
NACRES:
NA.32
Empfohlene Produkte
Form
crystalline
Qualitätsniveau
mp (Schmelzpunkt)
233-235 °C (dec.) (lit.)
SMILES String
N[C@@H](Cc1ccc(O)c(c1)[N+]([O-])=O)C(O)=O
InChI
1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1
InChIKey
FBTSQILOGYXGMD-LURJTMIESA-N
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Anwendung
3-Nitro-L-tyrosine has been used in:
- western blot analysis to quantify the nitrotyrosine levels in mice tissue protein
- Murashige–Skoog medium to treat wild type and mitogen-activated protein kinase 6 (mpk6)-2 mutant seedlings for inferring the connection between nitric oxide (NO) and MPK6 functions in the regulation of mitotic microtubule organization
- immunocytochemistry
Biochem./physiol. Wirkung
3-Nitro-L-tyrosine is an oxidant and cytotoxic agent. 3-Nitrotyrosine serves as a biological marker of proteins modified by nitrogen-free radical species in systemic autoimmunogenic conditions. It is a marker for oxidative damage mediated by peroxynitrite. Nitrotyrosine is associated with VEGF-C expression and lymph node metastasis in breast cancer. 3-Nitrotyrosine is produced due to oxidative/nitrosative stress-mediated chemical modifications such as nitration of proteins, which is observed in lung carcinogenesis.
Ähnliches Produkt
Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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