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N7271

Sigma-Aldrich

α(2→3)-Neuraminidase aus Streptococcus pneumoniae

buffered aqueous solution

Synonym(e):

Acyl-Neuraminyl-Hydrolase, Acylneuraminyl-Hydrolase, Receptor-destroying enzyme, Sialidase

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About This Item

CAS-Nummer:
9001-67-6
EC-Nummer:
3.2.1.18 (BRENDA, IUBMB)
MDL-Nummer:
MFCD01092203
UNSPSC-Code:
12352204
NACRES:
NA.32

Biologische Quelle

Streptococcus pneumoniae

Qualitätsniveau

100

Form

buffered aqueous solution

Konzentration

≥5 units/mL

Fremdaktivität

β-Galactosidase, α-mannosidase, β-hexosaminidase, α-fucosidase, and proteases, none detected

Versandbedingung

wet ice

Lagertemp.

2-8°C

Angaben zum Gen

Streptococcus pneumoniae R6 ... nanB(933504)

Verwandte Kategorien

Biochem./physiol. Wirkung

Releases α(2→3)-linked N-acetylneuraminic acid from complex oligosaccharides.

Verpackung

Provided with 5× reaction buffer (250 mM sodium phosphate, pH 6.0).

Einheitendefinition

One unit will hydrolyze 1μmole of 4-methylumbelliferyl α-D-N-acetylneuraminide per min at pH 5.0 at 37 °C.

Physikalische Form

Solution in 50 mM sodium phosphate, pH 7.5

Angaben zur Herstellung

Expressed in glycosidase-free hosts.

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H334

Gefahreneinstufungen

Resp. Sens. 1

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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The Medical journal of Australia, 198(7), 370-372 (2013-04-16)
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Dominic Meusch et al.
Nature, 508(7494), 61-65 (2014-02-28)
Tripartite Tc toxin complexes of bacterial pathogens perforate the host membrane and translocate toxic enzymes into the host cell, including in humans. The underlying mechanism is complex but poorly understood. Here we report the first, to our knowledge, high-resolution structures
Audu J Natala et al.
Journal of medical entomology, 50(1), 85-93 (2013-02-23)
Amblyomma variegatum F. are obligate hematophagous ectoparasites of livestock that serve as the vectors of Ehrlichia ruminantium (formerly known as Cowdria ruminantium), the causative agent of heartwater disease. In the light of the fact that they are blood-feeding, their salivary
Johan Nordholm et al.
The Journal of biological chemistry, 288(15), 10652-10660 (2013-03-01)
Interactions that facilitate transmembrane domain (TMD) dimerization have been identified mainly using synthetic TMDs. Here, we investigated how inherent properties within natural TMDs modulate their interaction strength by exploiting the sequence variation in the nine neuraminidase subtypes (N1-N9) and the
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