N3139

β-Nicotinamidadenin-Dinucleotidphosphat Hydrat

powder, BioReagent, suitable for cell culture

• Synonym(e): Triphosphopyridin-Nukleotid Natriumsalz Hydrat
• Empirische Formel (Hill-System): C₂₁H₂₇N₇NaO₁₇P₃ · xH₂O
• CAS-Nummer: 698999-85-8
• Molekulargewicht: 765.39 (anhydrous basis)
• MDL-Nummer: MFCD00150480
• UNSPSC-Code: 12352205
• PubChem Substanz-ID: 24897624
• NACRES: NA.75

Eigenschaften

• Produktlinie: BioReagent
• Assay: ≥98% (HPLC); ≥98% (spectrophotometric assay)
• Form: powder
• Methode(n): cell culture | mammalian: suitable
• mp (Schmelzpunkt): 175-178 °C (dec.) (lit.)
• Löslichkeit: H₂O: 50 mg/mL
• Lagertemp.: −20°C
• SMILES String: O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(OP(OC[C@H]3O[C@@H](N(C=N4)C5=C4C(N)=NC=N5)[C@H](OP(O)(O)=O)[C@@H]3O)([O-])=O)([O-])=O.O.[Na+]
• InChI: 1S/C21H28N7O17P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1
• InChIKey: CYQLUFJYVTUUFN-WUEGHLCSSA-M

Beschreibung

Anwendung

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate has been used in the purification and crystallization of CHORD–Sgt1 cytochrome b 5 reductases (CS–b5R). It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 medium for direct hepatic reprogramming using mouse embryonic fibroblasts (MEFs).

Biochem./physiol. Wirkung

Nicotinamide adenine dinucleotide phosphate (NADP) is an indispensable cofactor that participates in cellular redox reactions. It acts as a hydride-accepting coenzyme and participates in substrate oxidation reactions during metabolism.

Elektronenakzeptor

Verpackung

abgefüllt nach Gewicht des Feststoffs

Hinweis zur Analyse

Meets or exceeds NRC specifications and is comparable to any commercial preparation available.

Sonstige Hinweise

Dies ist die übliche Form von NADP. Nicht zu verwechseln mit 3′−NADP oder α-NADP!

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319
• P-Sätze: P280 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable