M9434
Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat
clone 14, tissue culture supernatant
Synonym(e):
Anti-MBP
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About This Item
Empfohlene Produkte
Biologische Quelle
rat
Qualitätsniveau
Konjugat
unconjugated
Antikörperform
tissue culture supernatant
Antikörper-Produkttyp
primary antibodies
Klon
14, monoclonal
Enthält
0.09% sodium azide
Speziesreaktivität
horse, chicken, human
Methode(n)
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
Isotyp
IgG
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Lagertemp.
−20°C
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... MBP(4155)
Allgemeine Beschreibung
Myelin basic protein (MBP) is part of the myelin sheath and is a calcium-dependent protein. It has six isoforms and the gene encoding it is localized on human chromosome 18q23.
Spezifität
Recognizes amino acids 36-50 of myelin basic protein.
Immunogen
bovine myelin basic protein.
Biochem./physiol. Wirkung
Myelin basic protein (MBP) associates with calmodulin and has been identified as an auto-antigen in multiple sclerosis (MS). It also inhibits the assembly of amyloid-β protein.
Angaben zur Herstellung
Generated by somatic cell hybridization of NS0 myeloma cells with spleen cells from an outbred rat immunized with bovine myelin basic protein.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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