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Merck

M7523

Sigma-Aldrich

Anti-Myosin (Skeletal) antibody produced in rabbit

enhanced validation

whole antiserum

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

whole antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Enthält

15 mM sodium azide

Speziesreaktivität

human

Erweiterte Validierung

independent
Learn more about Antibody Enhanced Validation

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20 using human or animal skeletal muscle
indirect immunofluorescence: 1:20 using human or animal sletetal muscle

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

Allgemeine Beschreibung

Myosin is a 480,000 dalton protein containing two identical heavy chains (200,000 daltons each) and four light chains (15,000-26,000 daltons). Myosin molecules consist of two major regions: tails (rods) and heads; they aggregate into filaments through the tail region. Multiple forms of myosin heavy chains exist for each muscle type; skeletal, cardiac, smooth and non-muscle isomyosin forms exist in different types of skeletal muscle, depending on the physiological function of the muscle.

Spezifität

Specifically labels the A bands of human and animal skeletal muscle. Does not stain human smooth muscle tissue.

Immunogen

whole myosin (heavy and light chains) from human skeletal muscle.

Anwendung

Anti-Myosin (Skeletal) antibody produced in rabbit has been used in:
  • immunohistochemistry
  • immunostaining
  • western blotting
  • immunofluorescence
  • immunolocalization
  • immunocytochemistry

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)
Western Blotting (1 paper)

Qualität

The antiserum has been treated to remove lipoproteins.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Xenotransplantation of human dental pulp stem cells in xn-plateletrich-009f plasma for the treatment of xn-fullthickness-sm6g articular cartilage defects in a rabbit model
Yanasse RH, et al.
Experimental and Therapeutic Medicine, 17(6), 4344-4356 (2019)
Hilda Merino et al.
Oxidative medicine and cellular longevity, 2018, 6043064-6043064 (2018-08-29)
Doxorubicin (Dox) is a potent chemotherapeutic drug known for its dose-dependent and serious adverse effects, such as cardiotoxicity and myotoxicity. Dox-induced cardiotoxicity (DIC) and muscle toxicity (DIMT) have been studied; however, the mechanisms of Dox-induced apoptosis in soleus muscle are
Tatiana Jazedje et al.
Journal of translational medicine, 7, 46-46 (2009-06-23)
The possibility of using stem cells for regenerative medicine has opened a new field of investigation. The search for sources to obtain multipotent stem cells from discarded tissues or through non-invasive procedures is of great interest. It has been shown
Mariane Secco et al.
Stem cells (Dayton, Ohio), 26(1), 146-150 (2007-10-13)
The identification of mesenchymal stem cell (MSC) sources that are easily obtainable is of utmost importance. Several studies have shown that MSCs could be isolated from umbilical cord (UC) units. However, the presence of MSCs in umbilical cord blood (UCB)
Multipotent Stem Cells from Umbilical Cord: Cord Is Richer than Blood!
Secco M, et al.
Stem Cells, 26(1), 146-150 (2008)

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