M1568

Mannose-Triflat

For PET imaging, ≥98% (TLC)

• Synonym(e): 1,3,4,6-Tetra-O-acetyl-2-O-trifluormethansulfonyl-β-D-mannopyranose, β-D-Mannopyranose 1,3,4,6-tetra-O-acetat 2-O-Trifluormethansulfonat, Mannosetriflat, TATM
• Empirische Formel (Hill-System): C₁₅H₁₉F₃O₁₂S
• CAS-Nummer: 92051-23-5
• Molekulargewicht: 480.36
• Beilstein: 4341413
• MDL-Nummer: MFCD00012353
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 24896669
• NACRES: NA.12

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98% (TLC)
• Form: powder
• Methode(n): PET imaging: suitable
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
• InChI: 1S/C15H19F3O12S/c1-6(19)25-5-10-11(26-7(2)20)12(27-8(3)21)13(14(29-10)28-9(4)22)30-31(23,24)15(16,17)18/h10-14H,5H2,1-4H3/t10-,11-,12+,13+,14-/m1/s1
• InChIKey: OIBDVHSTOUGZTJ-PEBLQZBPSA-N

Beschreibung

Allgemeine Beschreibung

Mannose triflate is a glucose analogue.

Anwendung

Mannose triflate is a well-known precursor for ¹⁸F-FDG synthesis for PET applications. The binding of ¹⁸F to the mannose triflate has been carried out via SN₂ nucleophilic substitution reaction. It is used in computational tomography, an imaging technique in early detection of cancer.

Sonstige Hinweise

This formulation of mannose triflate has reduced trace impurities that are known to cause lower synthetic yields.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)