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I8754

Sigma-Aldrich

L-allo-Isoleucin

≥99%

Synonym(e):

(2S,3R)-2-Amino-3-methyl-pentansäure

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About This Item

Empirische Formel (Hill-System):
C6H13NO2
CAS-Nummer:
1509-34-8
Molekulargewicht:
131.17
Beilstein:
1721791
EG-Nummer:
216-142-3
MDL-Nummer:
MFCD00066446
UNSPSC-Code:
12352209
eCl@ss:
32160406
PubChem Substanz-ID:
24896143
NACRES:
NA.26

product name

L-allo-Isoleucin,

Assay

≥99%

Form

powder

Farbe

white to off-white

mp (Schmelzpunkt)

285 °C

SMILES String

CC[C@@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5+/m1/s1

InChIKey

AGPKZVBTJJNPAG-UHNVWZDZSA-N

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Anwendung


  • Pseudomonas syringae pv. tomato DC3000 CmaL (PSPTO4723), a DUF1330 family member, is needed to produce L-allo-isoleucine, a precursor for the phytotoxin coronatine: This study demonstrates the essential role of L-allo-isoleucine in the synthesis of plant toxins, impacting plant pathology and biocontrol strategies (Worley et al., 2013).

Biochem./physiol. Wirkung

L-allo-Isoleucine may be used in studies on maple syrup urine disease.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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J E Baldwin et al.
The Biochemical journal, 301 ( Pt 2), 367-372 (1994-07-15)
Potential substrates for L-delta-(alpha-aminoadipoyl)-L-(cysteinyl)-D-valine (ACV) synthetase were initially identified using both the amino-acid-dependent ATP<-->pyrophosphate exchange reaction catalysed by the enzyme and the incorporation of 14C-radiolabelled cysteine and valine into potential peptide products. S-Carboxymethylcysteine was an effective substitute for alpha-aminoadipate and
U Wendel et al.
Pediatric research, 25(1), 11-14 (1989-01-01)
The nonprotein amino acid L-allo-isoleucine is formed endogenously in maple syrup urine disease patients from (R)-3-methyl-2-oxo-pentanoic acid. During strict metabolic balance, the plasma L-allo-isoleucine/L-isoleucine ratio correlates inversely with the residual activity of the branched-chain 2-oxoacid dehydrogenase in fibroblasts and thus
P Schadewaldt et al.
Biochemical medicine and metabolic biology, 41(2), 105-116 (1989-04-01)
Possible functional differences in the catabolism of the four branched-chain L-amino acids in maple syrup urine disease were assessed using cultured human skin fibroblast stains. Transamination and oxidative decarboxylation were comparatively studied in 90-min incubations with 1 mmole/liter of 1-14C-labeled
Mahesha M Poojary et al.
Food chemistry, 234, 236-244 (2017-05-30)
In this study, enzyme-assisted extraction was performed to extract umami taste and total free amino acids (FAAs) from the six different mushrooms including shiitake (Lentinus edodes), oyster (Pleurotus ostreatus), tea tree (Agrocybe aegerita) and, white, brown and portobello champignons (Agaricus
Chen Barazani et al.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 52, 101312-101312 (2020-03-23)
Laron Syndrome (LS), (OMIM# 262500), a rare recessively inherited disease caused by deletions or mutations of the GH receptor, gene characterized by dwarfism with low or undetectable serum IGF-I in the presence of high serum GH. In addition to dwarfism
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