H7890

L-Homoserinlacton -hydrochlorid

suitable for ligand binding assays

• Empirische Formel (Hill-System): C₄H₇NO₂ · HCl
• CAS-Nummer: 2185-02-6
• Molekulargewicht: 137.56
• MDL-Nummer: MFCD00058172
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24895811
• NACRES: NA.26

Eigenschaften

• product name: L-Homoserinlacton -hydrochlorid,
• Form: powder
• Qualitätsniveau: 200
• Methode(n): ligand binding assay: suitable
• Farbe: white
• Lagertemp.: −20°C
• SMILES String: Cl.N[C@H]1CCOC1=O
• InChI: 1S/C4H7NO2.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
• InChIKey: XBKCXPRYTLOQKS-DFWYDOINSA-N

Beschreibung

Allgemeine Beschreibung

L-Homoserine lactone (HSL), also called acyl-HSL, comprises a homoserine lactone ring and a fatty acyl side. The levels of acyl-HSL in bacteria is dictated by the availability of the substrates and acyl-homoserine lactones synthase.

Anwendung

L-Homoserine lactone hydrochloride has been used as an inhibitor for arterial smooth muscle contraction.

Biochem./physiol. Wirkung

L-Homoserine lactone inhibition reduces virulence factors and halts inflammation and tissue damage. In Pseudomonas aeruginosa it controls virulence factor production and biofilm formation. In Agrobacterium tumefaciens, it is essential for conjugal transfer.

Acylated L-Homoserine lactone(s) are used to study bacterial quorum-sensing signaling mechanisms.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)