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H3035

Sigma-Aldrich

Hydrocortison -acetat (Salz)

meets USP testing specifications

Synonym(e):

Hydrocortison 21-Acetat, 11β,17α,21-Trihydroxy-4-pregnen-3,20-dion-21-acetat, 17-α-Hydroxycorticosteronacetat, 17-Hydroxycorticosteron-21-acetat, 21-Acetoxy-4-pregnen-11β,17α-diol-3,20-dion, 4-Pregnen-11β,17α,21-triol-3,20-dion-21-acetat

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About This Item

Empirische Formel (Hill-System):
C23H32O6
CAS-Nummer:
50-03-3
Molekulargewicht:
404.50
Beilstein:
2066841
EG-Nummer:
200-004-4
MDL-Nummer:
MFCD00037714
UNSPSC-Code:
41116107
PubChem Substanz-ID:
24895547
NACRES:
NA.21

Agentur

USP/NF
meets USP testing specifications

Qualitätsniveau

200

mp (Schmelzpunkt)

223 °C (dec.) (lit.)

SMILES String

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChIKey

ALEXXDVDDISNDU-JZYPGELDSA-N

Angaben zum Gen

human ... NR3C1(2908) , SERPINA6(866)

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Dieser Artikel
P233B4559C1619
Piribedil maleate salt

P9233

Piribedil maleate salt

PD 168,077 maleate salt powder

P233

PD 168,077 maleate salt

BRL 44408 ≥98% (HPLC)

B4559

BRL 44408

CGS-9343B ≥98% (HPLC), powder

C1619

CGS-9343B

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

2-8°C

solubility

DMSO: >10 mg/mL, H2O: >10 mg/mL

solubility

DMSO: >10 mg/mL

solubility

H2O: soluble 15 mg/mL, clear

solubility

DMSO: >10 mg/mL

originator

Servier

originator

-

originator

GlaxoSmithKline

originator

Novartis

Gene Information

human ... DRD3(1814)

Gene Information

human ... DRD4(1815)

Gene Information

-

Gene Information

-

Anwendung

Hydrocortisone 21-acetate is used as a stabilized form of the glucocorticoid in studies on stress and homeostasis.

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H360Df,H373

Gefahreneinstufungen

Repr. 1B - STOT RE 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

    • Hier finden Sie alle aktuellen Versionen:

    Analysenzertifikate (COA)

    Lot/Batch Number
    SLCJ9335
    SLCH0501
    SLCG8478
    SLCD2195
    SLBX7231

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    B Ramírez Andrade et al.
    Journal of dairy science, 91(6), 2299-2306 (2008-05-20)
    Lactation artificially induced (ART) by steroid hormones and natural lactation (NAT) after lambing were compared in 2 dairy sheep breeds (Manchega and Lacaune) in 2 experiments conducted during winter and spring. In experiment 1, ART ewes (14 Manchega and 9
    Nunzia Falco et al.
    International journal of pharmaceutics, 441(1-2), 589-597 (2012-11-06)
    The objective of the present study was to develop an anti-inflammatory prolonged action formulation for local injection in prefilled syringes. Hydrocortisone acetate (HA) was selected as a model corticosteroid drug to be incorporated in poly(lactic-co-glycolic) (PLGA) microspheres. The formulation was
    Johanna Mandelin et al.
    Acta dermato-venereologica, 90(2), 170-174 (2010-02-20)
    A one-year, randomized, double-blind study was conducted in 80 patients with atopic dermatitis treated with tacrolimus ointment or a corticosteroid regimen (hydrocortisone acetate 1% ointment for head and neck, hydrocortisone butyrate 0.1% ointment for trunk and limbs) to compare efficacy
    Otto Chan et al.
    Disability and rehabilitation, 30(20-22), 1697-1708 (2008-07-09)
    To determine the effectiveness of high volume image guided injections (HVIGI) for chronic Achilles tendinopathy. We included in the study 30 consecutive patients (mean age 37.2 years, range 24 - 58 years) with Achilles tendinopathy for a mean of 35.8
    Sai H S Boddu et al.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 26(1), 37-48 (2010-02-13)
    This article describes the development and characterization of PLGA nanoparticles of dexamethasone (DEX), hydrocortisone acetate (HA), and prednisolone acetate (PA) suspended in thermosensitive gels indicated for the treatment of macular edema (ME). Nanoparticles were prepared by oil-in-water (O/W) emulsion and
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