H3023

20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid

≥90% (HPLC), liquid, Ras/MAP pathway activitor

• Synonym(e): 20-HETE, 20-Hydroxyarachidonic acid
• Empirische Formel (Hill-System): C₂₀H₃₂O₃
• CAS-Nummer: 79551-86-3
• Molekulargewicht: 320.47
• MDL-Nummer: MFCD00171542
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 24895546
• NACRES: NA.77

Eigenschaften

• product name: 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid, ~100 μg/mL in ethanol, ≥90% (HPLC)
• Assay: ≥90% (HPLC)
• Form: liquid
• Konzentration: ~100 μg/mL in ethanol
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: OCCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
• InChI: 1S/C20H32O3/c21-19-17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(22)23/h1,3-4,6-7,9-10,12,21H,2,5,8,11,13-19H2,(H,22,23)/b3-1-,6-4-,9-7-,12-10-
• InChIKey: NNDIXBJHNLFJJP-DTLRTWKJSA-N

Beschreibung

Biochem./physiol. Wirkung

20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid (20-HETE) is an arachidonic acid metabolite via cytochrome P4504A, that is an activator of the Ras/MAP (microtubule-associated protein) pathway. 20-HETE acid is a predominant arachidonic acid present in the kidney. It is involved in the regulation of sodium, potassium and chloride transport in the renal tubules. 20-HETE is often excreted in urine in the form of glucuronide conjugate and sometimes as free acids. Increased urine 20-HETE is observed during pregnancy in rats.

Verpackung

Packaged under argon.

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H319
• P-Sätze: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 57.2 °F - closed cup
• Flammpunkt (°C): 14.0 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)