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G1642
sn-Glycerol-3-phosphocholine Phosphodiesterase from mold
lyophilized powder, ≥5 units/mg protein
Synonym(e):
Glycerophosphorylcholine phosphodiesterase from mold
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About This Item
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.54
Empfohlene Produkte
Form
lyophilized powder
Qualitätsniveau
Spezifische Aktivität
≥5 units/mg protein
Zusammensetzung
Protein, ~40% Bradford
Lagertemp.
−20°C
Einheitendefinition
One unit will produce 1.0 μmole of choline from L-α-glycerophosphorylcholine, G4007, per min at pH 8.0 at 37 °C.
Physikalische Form
Lyophilized powder containing Tris buffer salt
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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J Florin-Christensen et al.
Biochemistry and molecular biology international, 47(2), 283-292 (1999-04-17)
The purification and characterization of a novel phosphodiesterase (PDE) is presented. The activity was detected in the extracellular medium of Tetrahymena thermophila cultures, by the release of p-nitrophenol from p-nitrophenylphosphocholine (PNPPC) with an acidic pH optimum. In cell homogenates, it
J Mitra et al.
Molecular and cellular biochemistry, 139(2), 101-108 (1994-10-26)
The rat uterine secretory enzyme glycerylphosphorylcholine (GPC) diesterase (EC 3.1.4.2) had been purified and characterized previously with respect to its mol. wt., size, amino acid, carbohydrate composition and estrogen inducible properties. This enzyme is observed to have exclusive specificity for
B M Ross et al.
Lipids, 30(12), 1075-1081 (1995-12-01)
Brain levels of glycerophosphodiesters, including glycerophosphocholine (GPC) and glycerophosphoethanolamine (GPE), are altered in many human central nervous system disorders. Although much information is available on the enzymes responsible for the formation of these phospholipid metabolites, little information is known regarding
Egidio Iorio et al.
Cancer research, 70(5), 2126-2135 (2010-02-25)
Altered phosphatidylcholine (PC) metabolism in epithelial ovarian cancer (EOC) could provide choline-based imaging approaches as powerful tools to improve diagnosis and identify new therapeutic targets. The increase in the major choline-containing metabolite phosphocholine (PCho) in EOC compared with normal and
Carmelina D Anfuso et al.
Lipids, 38(1), 45-52 (2003-04-03)
In pericytes from bovine retina, the enzyme glycerophosphocholine phosphodiesterase, catalyzing the hydrolysis of sn-glycero-3-phosphocholine to glycero-3-phosphate and choline, has been characterized with respect to pH optimum, metal ion dependence, Km, inhibitors, and subcellular localization. In these cells, the natural substrate
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