F6127

Fludrocortisonacetat

≥98%

• Synonym(e): 9α-Fluor-11β,17α,21-trihydroxy-4-pregnen-3,20-dion-acetat, 9-Fluor-hydrocortison-acetat, 9-Fluorcortisol-acetat
• Empirische Formel (Hill-System): C₂₃H₃₁FO₆
• CAS-Nummer: 514-36-3
• Molekulargewicht: 422.49
• EG-Nummer: 208-180-4
• MDL-Nummer: MFCD00864160
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24894899
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 100
• Sterilität: non-sterile
• Assay: ≥98%
• Form: powder
• Löslichkeit: acetone: 50 mg/mL, clear, colorless to light yellow
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
• InChI: 1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
• InChIKey: SYWHXTATXSMDSB-GSLJADNHSA-N
• Angaben zum Gen: human ... NR3C2(4306)

Beschreibung

Allgemeine Beschreibung

Fludrocortisone acetate is secreted by adrenal cortex. It increases the reabsorption of sodium and secretion of potassium and hydrogen. Fludrocortisone is used to treat cerebral salt wasting syndrome and adrenal insufficiency. Fludrocortisone improves the sensitivity of blood vessels to catecholamines and increases the blood volume.

Biochem./physiol. Wirkung

Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H302,H361
• P-Sätze: P201 - P301 + P312 + P330 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Repr. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable