F1428

Fenvalerat

≥97%

• Synonym(e): α-Cyano-3-phenoxybenzyl α-(4-chlorphenyl)­iso­valerat
• Empirische Formel (Hill-System): C₂₅H₂₂ClNO₃
• CAS-Nummer: 51630-58-1
• Molekulargewicht: 419.90
• Beilstein: 2025982
• MDL-Nummer: MFCD00055324
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329799681
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥97%
• Lagertemp.: −20°C
• SMILES String: CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
• InChI: 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
• InChIKey: NYPJDWWKZLNGGM-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.

Anwendung

Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.

Biochem./physiol. Wirkung

Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.

Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.

Typ II Pyrethroid. Potenter Inhibitor von Calcineurin (Proteinphosphatase 2B).

Angaben zur Herstellung

Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H301,H315,H319,H335,H410
• P-Sätze: P261 - P264 - P273 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable