E8515

β-Oestradiol-3-benzoat

≥97%

• Synonym(e): 1,3,5(10)-Estratrien-3,17β-diol-3-benzoat, 3,17β-Dihydroxy-1,3,5(10)-estratrien-3-benzoat, 3-Benzoyloxy-17β-oestrol
• Empirische Formel (Hill-System): C₂₅H₂₈O₃
• CAS-Nummer: 50-50-0
• Molekulargewicht: 376.49
• Beilstein: 3107526
• EG-Nummer: 200-043-7
• MDL-Nummer: MFCD00003692
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 24894677
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥97%
• mp (Schmelzpunkt): 191-198 °C (lit.)
• SMILES String: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OC(=O)c5ccccc5)ccc24
• InChI: 1S/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1
• InChIKey: UYIFTLBWAOGQBI-BZDYCCQFSA-N

Beschreibung

Anwendung

β-Estradiol 3-benzoate has been used:to mimic estradiol in rat during the oestrous cycle in rats. It has also been used along with progesterone for the induction of sexual receptivity in female rat.

Verwendet in Studien zum allgemeinen Steroidmetabolismus und Basisabklärungen für anaboles Steroid-Screening bei Sportlern

Biochem./physiol. Wirkung

β-Estradiol 3-benzoate is a synthetic estrogen. It favors breast cancer progression. It is an endocrine disrupting chemicals. It interacts with endocrine system and cause harmful effect on reproduction in animals and humans. It binds to estrogen receptors and favors tumor metastatis in breast, prostate and bone cells.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H351,H360FD
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Carc. 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges