E4375

(−)-Epinephrin -(+)-bitartratsalz

solid, adrenergic receptor agonist

• Synonym(e): L-3,4-Dihydroxy-α-(methylaminomethyl)benzylalkohol-Wasserstoff D -bitartrat (Salz), L-Adrenalin -(+)-bitartratsalz, L-Adrenalin D-bitartrat, L-Epinephrin D-bitartrat
• Empirische Formel (Hill-System): C₉H₁₃NO₃ · C₄H₆O₆
• CAS-Nummer: 51-42-3
• Molekulargewicht: 333.29
• EG-Nummer: 200-097-1
• MDL-Nummer: MFCD00035077
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24277774
• NACRES: NA.77

Eigenschaften

• product name: (−)-Epinephrin -(+)-bitartratsalz, solid
• Form: solid
• Qualitätsniveau: 200
• Farbe: white
• Löslichkeit: H₂O: soluble; alcohol: soluble
• Lagertemp.: 2-8°C
• SMILES String: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• InChIKey: YLXIPWWIOISBDD-NDAAPVSOSA-N
• Angaben zum Gen: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

Beschreibung

Allgemeine Beschreibung

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.

Anwendung

(-)Epinephrine (+)-bitartrate salt has been used:

• to test the possible existence of β-adrenergic vasodilation
• to infuse into the adipose region to minimize blood loss and tissue contamination
• as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates
• in the measurement of total superoxide dismutase (tSOD) enzymatic activity

Biochem./physiol. Wirkung

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.

Adrenergischer Rezeptoragonist.

Leistungsmerkmale und Vorteile

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Vorsicht

Light sensitive

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 1 Oral
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges