D2531

Dextromethorphan -hydrobromid Monohydrat

≥99% (TLC)

• Synonym(e): (9S,13S,14S)-3-Methoxy-17-methylmorphinan -hydrobromid
• Empirische Formel (Hill-System): C₁₈H₂₅NO · HBr · H₂O
• CAS-Nummer: 6700-34-1
• Molekulargewicht: 370.32
• Beilstein: 6453793
• MDL-Nummer: MFCD02173901
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 57654086
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥99% (TLC)
• Form: powder
• SMILES String: Br[H].[H]O[H].[H][C@]12CCCC[C@]13CCN(C)[C@H]2Cc4ccc(OC)cc34
• InChI: 1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1
• InChIKey: STTADZBLEUMJRG-IKNOHUQMSA-N
• Angaben zum Gen: human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , SIGMAR1(10280)

Beschreibung

Anwendung

Dextromethorphan hydrobromide monohydrate has been used as a substrate for cytochrome P450 2D6 enzyme action, in potassium phosphate buffer for measuring P450 activity and is used in enzyme inhibition studies.

Biochem./physiol. Wirkung

Dextromethorphan hydrobromide is an allosteric antagonist at N-methyl D- aspartate (NMDA)-controlled ion channels and antagonist at voltage-dependent channels. Dextromethorphan hydrobromide is useful in treating dry cough.

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H301,H411
• P-Sätze: P264 - P270 - P273 - P301 + P310 - P391 - P405
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Chronic 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)