D1881

Dexamethason-21-Acetat

≥99%

• Synonym(e): 9α-Fluor-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion-21-acetat, 9α-Fluor-16α-methyl-prednisolon-21-acetat, Prednisolon F-acetat
• Empirische Formel (Hill-System): C₂₄H₃₁FO₆
• CAS-Nummer: 1177-87-3
• Molekulargewicht: 434.50
• Beilstein: 2342608
• EG-Nummer: 214-646-8
• MDL-Nummer: MFCD00027407
• UNSPSC-Code: 51422333
• PubChem Substanz-ID: 24893562
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥99%
• Form: powder
• Lagertemp.: 2-8°C
• SMILES String: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• InChIKey: AKUJBENLRBOFTD-RPRRAYFGSA-N
• Angaben zum Gen: human ... NR3C1(2908)

Beschreibung

Anwendung

Dexamethasone 21-acetate has been used:

• as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
• as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
• as a component of the complete medium for the culturing of porcine hepatocytes

Biochem./physiol. Wirkung

Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360FD
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves