C3412

Cyproteronacetat

≥98%

• Synonym(e): 6-Chlor-1β,2β-dihydro-17-hydroxy-3′H-cyclopropa[1,2]pregna-1,4,6-trien-3,20-dion-acetat
• Empirische Formel (Hill-System): C₂₄H₂₉ClO₄
• CAS-Nummer: 427-51-0
• Molekulargewicht: 416.94
• EG-Nummer: 207-048-3
• MDL-Nummer: MFCD00864671
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 24278309
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98%
• Form: powder
• Lagertemp.: 2-8°C
• SMILES String: [H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C
• InChI: 1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1
• InChIKey: UWFYSQMTEOIJJG-FDTZYFLXSA-N
• Angaben zum Gen: human ... AR(367) , NR3C1(2908) , PGR(5241) ; mouse ... Nr3c1(14815) ; rat ... Ar(24208)

Beschreibung

Anwendung

Cyproterone acetate has been used to study its effects on insulin-like growth factor I secretion.

Biochem./physiol. Wirkung

Cyproterone acetate is a synthetic steroid and an androgen antagonist. It is a potent inhibitor of leukocyte migration through endothethial cell monolayers. Cyproterone acetate acts as a liver tumor promoter in experimental animal model. Liver tumor promotion appears to be female gender-specific, as formation of an active metabolite that forms DNA adducts.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H312 + H332,H351
• P-Sätze: P202 - P261 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges