B8684

Bambuterol -hydrochlorid

>98% (HPLC), powder

• Synonym(e): Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester
• Lineare Formel: C₁₈H₂₉N₃O₅ · HCl
• CAS-Nummer: 81732-46-9
• Molekulargewicht: 403.90
• MDL-Nummer: MFCD03427293
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329773137
• NACRES: NA.77

Eigenschaften

• Assay: >98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: off-white
• Löslichkeit: H₂O: soluble ~33 mg/mL
• Ersteller: AstraZeneca
• SMILES String: Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C
• InChI: 1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H
• InChIKey: LBARATORRVNNQM-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Bambuterol is present in various tissues, like , intestine, lungs, liver and heart. It is also found in serum.

Anwendung

Bambuterol hydrochloride has been used as a β2-adrenergic receptor (β2-AR) agonist to study its effects on graft versus host disease (GVHD) while preserving the graft-versus-tumor (GvT) effect. It has also been used in the preparation of bambuterol-poly vinyl chloride (Bb-PVC) membrane sensors for the determination of bambuterol in the pharmaceutical dosage form.

Biochem./physiol. Wirkung

Bambuterol hydrochloride is used for prophylaxis and also to treat chronic bronchitis and chronic asthma in pediatrics.

β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)