B8556
Hemocyanin from mollusk
buffered aqueous solution
Synonym(e):
Blue Carrier®
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About This Item
Empfohlene Produkte
Biologische Quelle
Concholepas sp. (Concholepas concholepas )
Qualitätsniveau
Form
buffered aqueous solution
Methode(n)
bioconjugation: suitable
Lagertemp.
2-8°C
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Anwendung
Blue Carrier is an oxygen-carrying protein isolated from the hemolymph of the mollusk Concholepas concholepas. It is highly immunogenic, useful as a carrier protein for the production of antibodies to small molecules. An example of the protocol is given in reference to production of antibodies to gizzerosine.
Hemocyanin is a carrier protein used in antibody production. It has been used to promote antibody production against haptins and peptides, in therepy for bladder carcinoma, and has a component in vaccines for cancer.
Biochem./physiol. Wirkung
Highly soluble carrier protein used in antibody production
Physikalische Form
100 mg in 0.5 mL of 0.15 M NaCl, 0.1 M sodium phosphate, pH 7.2
Rechtliche Hinweise
Blue Carrier is a registered trademark of Biosonda S.A.
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Harold Oliva et al.
Hybridoma and hybridomics, 21(5), 365-374 (2002-12-10)
We studied the reactivity of mouse monoclonal antibodies (MAbs) against the hemocyanin from the Chilean marine gastropod Concholepas concholepas (CCH). This protein has been successfully used as a carrier to produce antibodies to haptens and peptides. All MAbs (13) belonging
M I Becker et al.
Hybridoma, 17(4), 373-381 (1998-10-28)
This study is the first report of the development of monoclonal antibodies (MAbs) against gizzerosine (GZ), one of the causative agents of black vomit, a serious poultry disease. Balb/c mice were immunized with different GZ conjugates; the most immunogenic conjugate
Bruno Moltedo et al.
The Journal of urology, 176(6 Pt 1), 2690-2695 (2006-11-07)
We determined the antitumor properties of a newly available hemocyanin obtained from the Chilean gastropod Concholepas concholepas (Biosonda Corp., Santiago, Chile) in a syngeneic heterotopic mouse bladder carcinoma model. Since keyhole limpet hemocyanin (Pierce, Rockford, Illinois) is used increasingly in
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects.
Arancibia S., et al.
European Journal of Immunology (2011)
Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Daiana Guillen et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 674-675 (2014-10-14)
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