Alle Fotos(5)
Wichtige Dokumente
A3509
2-Aminopurin
≥99%
Synonym(e):
2-AP
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Alle Fotos(5)
About This Item
Empirische Formel (Hill-System):
C5H5N5
CAS-Nummer:
Molekulargewicht:
135.13
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51
Empfohlene Produkte
Biologische Quelle
synthetic
Qualitätsniveau
Assay
≥99%
Form
powder
mp (Schmelzpunkt)
280-282 °C (lit.)
Lagertemp.
2-8°C
SMILES String
Nc1ncc2[nH]cnc2n1
InChI
1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)
InChIKey
MWBWWFOAEOYUST-UHFFFAOYSA-N
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Anwendung
2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).
2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes.
Biochem./physiol. Wirkung
2-Aminopurine (2AP) is an analog of guanosine and adenosine, which can base pair with cytosine and thymine. It is used as a fluorescent probe in nucleic acid structure and dynamics. 2-Aminopurine (2-AP) inhibits double-stranded RNA-dependent protein kinase, protein kinase R (PKR).
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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